Resuscitation with hydroxyethyl starch 130/0.4 versus lactated Ringer on hemorrhage following a liver trauma in swine

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منابع مشابه

Initial administration of hydroxyethyl starch vs lactated Ringer after liver trauma in the pig.

BACKGROUND This study tested the circulatory effectiveness of post-trauma administration of a large intravascular volume expander, hydroxyethyl starch 130/0.4 (HES), vs standard lactated Ringer's solution (RL). METHODS Liver injury was inflicted in 14 pigs [31 (4) kg; mean (sd)] and treatment simulated an acute pre-hospital event: after a standard first-respond delay (7 min), volume administr...

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Comparison of the effects of lactated Ringer solution with and without hydroxyethyl starch fluid resuscitation on gut edema during severe splanchnic ischemia.

The type of fluid used during resuscitation may have an important impact on tissue edema. We evaluated the impact of two different regimens of fluid resuscitation on hemodynamics and on lung and intestinal edema during splanchnic hypoperfusion in rabbits. The study included 16 female New Zealand rabbits (2.9 to 3.3 kg body weight, aged 8 to 12 months) with splanchnic ischemia induced by ligatio...

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Hydroxyethyl starch is superior to lactated Ringer as a replacement fluid in a pig model of acute normovolaemic haemodilution.

BACKGROUND Tissue tolerance to oxygen privation during acute normovolaemic haemodilution with different fluids remains unclear. We tested the hypothesis that hydroxyethyl starch (HES) is superior to lactated Ringer's solution in pigs for preserving tissue perfusion during acute normovolaemic haemodilution. METHODS Twenty-four animals were randomized into control, lactated Ringer's solution an...

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Hydroxyethyl starch versus Ringer solution in cardiopulmonary bypass prime solutions (a randomized controlled trial)

BACKGROUND In our study we compared the Ringer solution, which is the standard prime solution of our department, with the HES (Hydroxyethyl starch) 130-0.4 solution, which can be a potential alternative prime solution with an indispensable material for the cardio-pulmonary bypass applications. METHODS 140 patients undergoing to CABG (Coronary Artery Bypass Graft surgery) were electively enrol...

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Hydroxyethyl starch in patients with trauma.

Editor—The Fluids in Resuscitation of Severe Trauma (FIRST) randomized trial conducted by James and colleagues compared hydroxyethyl starch (HES) 130/0.4 with 0.9% saline in the resuscitation of 115 patients with severe blunt or penetrating trauma at a single centre in South Africa. In blunt trauma, which accounts for 86–97% of all traumatic injuries in Europe, 3 no differences were found betwe...

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ژورنال

عنوان ژورنال: The FASEB Journal

سال: 2008

ISSN: 0892-6638,1530-6860

DOI: 10.1096/fasebj.22.1_supplement.1227.1